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Submitted: 22 April 2014 Modified: 04 June 2014
HERDIN Record #: NCR-OLFU-14042216113058

Lipid lowering activity of Capsicum annuum (Bell pepper) extract in hyperlipidemic Oryctolagus cuniculus (Dwarf netherland rabbit).

Jose Jurel M. Nuevo

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The primary point of the investigation was to determine whether Capsicum annuum extract can effectively reverse the hyperlipidemia induced to Oryctolagus cuniculus (Dwarf Netherland Rabbit). Capsicum annuum was chosen as the subject of this study for it belongs to the Family Capsaicin which other members were known to decrease high cholesterol levels contributing to several cardiovascular diseases based on previous research studies. This study employed the experimental research method. To establish the effect of Capsicum annuum, six rabbits were utilized. The researchers established the blood cholesterol baseline of the rabbits by feeding a non-fat diet for a period of three days. After testing for the baseline, the rabbits were induced with a fatty diet consisting of pellets having 3.5% crude fat for three days and cholesterol determination was repeated. The six rabbits were then divided into two groups randomly. The first group was fed with a fatty diet with the treatment of 5 mL of Capsicum annuum extract for three days while the second group was fed with a fatty diet without Capsicum annuum extract. After the experimental phase, a post-cholesterol determination was conducted to determine if there was a change in the rabbits' blood cholesterol levels. The post-cholesterol results showed that the first group fed with fatty diet with the Capsicum annuum extract had a decreased blood cholesterol level compared to the baseline while the second group fed with a fatty diet without Capsicum annuum extract had an increase in blood cholesterol level. Therefore, there is a significant difference in the blood cholesterol level of Oryctolagus cuniculus fed with a fatty meal without Capsicum annuum extract and fatty meal with Capsicum annuum extract. These findings suggest the anti-hyperlipidemic activity of Capsicum annuum extract, which may be used as healthy regimen in individuals who are high risk for cardiovascular diseases associated with hyperlipidemia.

Publication Type
Journal
Publication Sub Type
Journal Article, Original
Title
Fatima University Research Journal
Frequency
Annual
Publication Date
2008-2009
Issue
1
Page(s)
31-33

Objectives

To test the effectiveness of Capsicuum annuum (Bell Pepper) extract in lowering blood cholesterol level of Oryctolagus cuniculuc (Dwarf Netherland rabbit)

LocationLocation CodeAvailable FormatAvailability
Our Lady of Fatima University Fulltext Print Format
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